SCIENTIFIC PUBLICATIONS ON JOBELYN & OTHER PRODUCTS

 

Ayuba GI, Jensen GS, Benson KF, Okubena AM, Okubena O. Clinical efficacy of a West African sorghum bicolor-based traditional herbal preparation Jobelyn shows increased hemoglobin and CD4+ T-lymphocyte counts in HIV-positive patients. J Altern Complement Med. 2014 Jan;20(1):53-6. doi: 10.1089/acm.2013.0125. Epub 2013 Nov 27. PubMed PMID: 24283768

Geera B, Ojwang LO, Awika JM. New highly stable dimeric 3-deoxyanthocyanidin pigments from sorghum bicolor leaf sheath. J Food Sci. 2012 May;77(5):C566-72. doi: 10.1111/j.1750-3841.2012.02668.x. Epub 2012 Apr 10. PubMed PMID: 22489620

Benson KF, Beaman JL, Ou B, Okubena A, Okubena O, Jensen GS. West African Sorghum bicolor leaf sheaths have anti-inflammatory and immune-modulating properties in vitro. J Med Food. 2013 Mar;16(3):230-8. doi: 10.1089/jmf.2012.0214. Epub 2013 Jan 5. PubMed PMID: 23289787

Umukoro S, Adrian Omogbiya I, Taghogho Eduviere A. Evaluation of the Effect of Jobelyn® on Chemoconvulsants- Induced Seizure in Mice. BCN. 2013; 4 (2) 4 (2) :19-23 URL http://bcn.iums.ac.ir/browse.php?a_code=A-10-151&slc_lang=en&sid=1

Umukoro S, Ugbomah A, Aderibigbe A, Eduviere A, Omogbiya A. Antioxidant Property of Jobelyn as the Possible Mechanism Underlying its Anti-amnesic Activity in Rodents. BCN. 2013; 4 (1) 4 (1) :42-49 URL http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-139&slc_lang=en&sid=1

Omogbiya IA, Umukoro S, Aderibigbe AO, Bakre AG. Jobelyn® pretreatment ameliorates symptoms of psychosis in experimental models. J Basic Clin Physiol Pharmacol. 2013;24(4):331-6. doi: 10.1515/jbcpp-2012-0073. PubMed PMID: 23412872

Umukoro S, Omogbiya IA, Eduviere TA. Effect of Jobelyn® on intruder- and isolation-induced aggressive behavior in mice. J Basic Clin Physiol Pharmacol. 2013;24(4):263-9. doi: 10.1515/jbcpp-2012-0069. PubMed PMID: 23729562

Toxicological Profiles of Commercial Herbal Preparation, Jobelyn® nternational Journal of Health Research, December 2009; 2(4): 369-374 © Poracom Academic Publishers. All rights reserved. Available at http://www.ijhr.orgR

The influence of African Herbal Formula on the haematological parameters of trypanosome infected rats VI Okochi, J Okpuzor, MO Okubena, AK Awoyemi African Journal of Biotechnology Vol.2(9) 2003: 312-316

Response of Trypanosoma brucei brucei-induced anaemia to a commercial herbal preparation ……….. 4 African Journal of Biotechnology Vol. 2 (9), pp. 307‐311, September 2003

Thermal stability of 3-deoxyanthocyanidin pigments Liyi Yang , Linda Dykes , Joseph M. Awika Journal of Food Chemistry http://dx.doi.org/10.1016/j.foodchem.2014.03.105

Umukoro , A. T. Eduviere , A. C. Aladeokin , A. Olugbemide on Antidepressant-like Property of Jobelyn ® , an African Unique Herbal Formulation in Mice. Drug Res (Stuttg). 2014 Mar;64(3):146-50. doi: 10.1055/s-0033-1354366. Epub 2013 Sep 3.

 

Umukoro S, Oluwole OG, Eduviere AT, Adrian OI, Ajayi AM.Jobelyn® exhibited anti-inflammatory, antioxidant, and membrane-stabilizing activities in experimental models.J Basic Clin Physiol Pharmacol. 2015 May 28. pii: /j/jbcpp.ahead-of-print/jbcpp-2014-0113/jbcpp-2014-0113.xml. doi: 10.1515/jbcpp-2014-0113.

 

Tayo AO, Dosunmu AO, Akinola IO, Adewunmi A, Oloyede OA, Akinbami AA, Osikomaiya BI, Makanjuola SB An open-label, randomized, parallel-group comparative study of the efficacy of sorghum bicolor extract in preoperative anemia.

 

Samira BL. Makanjuola, Doyin Dosunmu, Louis Ajonuma, Abiodun Ogundaini and Olajuwon Okubena Newly isolated compounds from West African Sorghum bicolor leaf sheaths Jobelyn® show potential in cancer immunosurveillanceNewly isolated compounds from West African Sorghum bicolor leaf sheaths Jobelyn® show potential in cancer immunosurveillance

 

Dosunmu A. O. et al., Journal Of Harmonized Research in Medical & Health Sci.3(4), 2016, 3(4),296-302The short time effect of extract of Sorghum bicolor (Jobelyn) on the haematological parameters of Patients with Sickle Cell Anemia.

Dosunmu A. O. et al., Journal Of Harmonized Research in Medical & Health Sci.3(4), 2016, 3(4),296-302The short time effect of extract of Sorghum bicolor (Jobelyn) on the haematological parameters of Patients with Sickle Cell Anemia.

John, R.; Abolaji, A.O.; Adedara, A.O.; Ajayi, A.M.; Aderibigbe, A.O.; Umukoro, S.  Jobelyn® extends the life span and improves motor function in Drosophila melanogaster exposed to lipopolysaccharide via augmentation of antioxidant status. Metabolic Brain Disease 2022, 37, 1031-1040.

 

TABLE OF PUBLISHED RESEARCH STUDIES FOR JOBELYN
1. Adebayo, A.H.; Yakubu, O.F.; Egbung, G.E.; Williams, O.I.; Okubena, O. Sub-acute toxicological effects of Jobelyn® on pregnant albino rats American Institute of Physics 2018, 1954:030018 doi.org/10.1063/1.5033398.
2. Okubena, O.; Makanjuola, S.; Ajonuma, L.C.; Dosunmu, A.; Umukoro, S.; Erah, P.O. The West African Sorghum bicolor leaf sheath extract Jobelyn® and its diverse therapeutic potentials. MOJ Drug Design & Development Therapy 2018, 2, 1-10. DOI: 10.15406/mojddt.2018.02.00025.
3. Makanjuola, S.B.L.; Ogundaini, A.O.; Ajonuma, L.C.; Dosunmu, A. Apigenin and apigeninidin isolates from the Sorghum bicolor leaf targets inflammation via cyclooxygenase‐2 and prostaglandin‐E2 blockade. Clin Transplant. 2018, 21, 1487‐
4. Okochi VI, Okpuzor J, Okubena MO, Awoyemi AK. The influence of African herbal formular on the haematological parameters of trypanosome infected rats. J. Biotech. 2003, 2, 312–316.
5. Erah, P.O.; Asonye, C.C, Okhamafe, A.O. Response of trypanosoma brucei-induced anaemia to a commercial herbal preparation. Afr. J. Biotechnol, 2003, 2, 307–311.
6. Nnaji, M. How an African-made dietary supplement promises to revolutionize medical treatment. The African Courier (Germany). https://www.theafricancourier.de/africa/
7. Drug Dictionary of the National Cancer Institute, USA (https://www.cancer.gov/publications/dictionaries/cancer-drug/def/sorghum-bicolor-supplement
8. Umukoro, S.; Oghwere, E.E.; Ben-Azu, B.; Owoeye, O.; Ajayi, A.M.; Omorogbe, O.; Okubena, O. Jobelyn® ameliorates neurological deficits in rats with ischemic stroke through inhibition of release of pro-inflammatory cytokines and NF-ĸB signaling pathway Pathophysiology 2018, 26, 77-88.
9. Benson, K.F.; Beaman, J.L.; Ou, B.; Okubena, A.; Okubena, O.; Jensen G.S. West African Sorghum bicolor leaf sheaths have anti-inflammatory and immune-modulating properties in vitro. Journal of Medicinal Foods 2013, 16, 230–238.
10. Umukoro, S.; Oghwere, E.E.; Ben-Azu, B.; Owoeye, O.; Ajayi, A.M.; Omorogbe, O.; Okubena, O. Jobelyn® ameliorates neurological deficits in rats with ischemic stroke through inhibition of release of pro-inflammatory cytokines and NF-ĸB signaling pathway Pathophysiology 2018, 26, 77-88.
11. Oyinbo, C.A.; Dare, W.N.; Avwioro, O.G.; Igbigbi, P.S. Neuroprotective effect of Jobelyn® in the hippocampus of alcoholic rat is mediated in part by alterations in GFAP and NF protein expressions. Advances in Biological Research 2015, 9, 305-317.
12. Ayuba, G.I.; Jensen, G.S.; Benson, K.F.; Okubena, A.M.; Okubena, O.  Clinical efficacy of a West African Sorghum bicolor-based traditional herbal preparation Jobelyn shows increased hemoglobin and CD4+ T-lymphocyte counts in HIV-positive patients.  J Altern Complement Med. 2014, 20, 53–56.
13. Tayo ,  A.O.;  Dosunmu, O.;  Akinola  1 ,  I.O.; Adewunmi, A.;  Oloyede , O.A.; Akinbami,  A.A.; Osikomaiya , B.I.; Makanjuola, S.B.L. An open-label, randomized, parallel-group comparative study of the efficacy of Sorghum bicolor extract in preoperative anemia. Nutrition. 2007, 33, 113–117.
14. Umukoro, S.; Oluwole, O.G.;  Eduviere, A.T.;  Omogbiya,  A.;   Ajayi,  A.M. Jobelyn® exhibited anti-inflammatory, antioxidant, and membrane-stabilizing activities in experimental models, J. Basic Clin. Physiol. Pharmacol. 2015, 26, 501–508.
15. Omorogbe, O.; Ajayi, A.M.; Ben-Azu, B.; Oghwere, E.E.;  Adebesin, A.;  Aderibigbe, A.O.; Okubena, O.; Umukoro, S. Jobelyn® attenuates inflammatory responses and neurobehavioural deficits associated with complete Freund-adjuvant-induced arthritis in mice. & Pharmacother. 2018, 98, 585–593.
16. Oyinbo, C.A.; Igbigbi, P.S.; Avwioro, O.G. Jobelyn®supplement lowered neuronal degeneration: significance of altered p53 and ɤ-Enolase protein expressions in prefrontal cortex of rat exposed to ethanol. Annals of Neurosciences 2016, 23, 139–148.
17. Umukoro, S.; Ugbomah, A.; Aderibigbe, A.; Omogbiya, A. Antioxidant property of Jobelyn® as the possible mechanism underlying its anti-amnesic effect in rodents. Basic and Clinical Neurosci. 2013, 4, 42-49.
18. John, R.; Abolaji, A.O.; Adedara, A.O.; Ajayi, A.M.; Aderibigbe, A.O.; Umukoro, S. Jobelyn® extends the life span and improves motor function in Drosophila melanogaster exposed to lipopolysaccharide via augmentation of antioxidant status. Metabolic Brain Disease 2022, 37, 1031-1040.
19. Makanjuola, S.B.L.;   Dosunmu,  D.;   Ajonuma, L.;   Ogundaini,  A.; Okubena, O. Newly isolated compounds                from West African Sorghum bicolor leaf sheaths Jobelyn® show potential in cancer immunosurveillance. J. Cancer Res. & Ther. 2016,  4, 31-37.
20. Umukoro, S.; Omorogbe, O.; Aluko, O.M.; Eduviere, T.A.; Owoeye, O.; Oluwole, O.G. Jobelyn, a sorghum-based nutritional supplement attenuates unpredictable chronic mild stress-induced memory deficits in mice. Journal of Behavioral and Brain Sci. 2015, 5, 586-597.
27.Umukoro, S.; Eduviere, A.T.; Aladeokin, A.C.; Olugbemide, A.  Antidepressant-like property of Jobelyn® an African unique herbal formulation in mice. Drug Res. 2014, 64, 146-150.
28.Bhimalingeswarappa Geera, Leonnard O. Ojwang, and Joseph M. Awika …….New Highly Stable Dimeric 3-Deoxyanthocyanidin Pigments from Sorghum bicolor Leaf Sheath……..Journal of Food Science _ Vol. 77, Nr. 5, 2012 doi: 10.1111/j.1750-3841.2012.02668.x…………………..
29.Itivere Adrian Omogbiya, Adegbuyi Oladele Aderibigbe and Adewale Ganiyu Bakre Jobelyn pretreatment ameliorates symptoms of psychosis in experimental models DOI 10.1515/jbcpp-2012-0073 J Basic Clin Physiol Pharmacol 2013
30. Thermal stability of 3-deoxyanthocyanidin pigments Liyi Yang , Linda Dykes , Joseph M. Awika Journal of Food Chemistry http://dx.doi.org/10.1016/j.foodchem.2014.03.105
31. Toxicological Profiles of Commercial Herbal Preparation, Jobelyn® nternational Journal of Health Research, December 2009; 2(4): 369-374 © Poracom Academic Publishers. All rights reserved. Available at http://www.ijhr.orgR
32. Dosunmu A. O. et al., Journal Of Harmonized Research in Medical & Health Sci.3(4), 2016, 3(4),296-302The short time effect of extract of Sorghum bicolor (Jobelyn) on the haematological parameters of Patients with Sickle Cell Anemia.

Dosunmu A. O. et al., Journal Of Harmonized Research in Medical & Health Sci.3(4), 2016, 3(4),296-302The short time effect of extract of Sorghum bicolor (Jobelyn) on the haematological parameters of Patients with Sickle Cell Anemia.

 

 

JOBELYN REFERENCES ON THE INTERNET:

JOBELYN ABSTRACTS ON THE INTERNET AMENDED

 

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