{"id":6749,"date":"2021-12-27T23:45:48","date_gmt":"2021-12-27T23:45:48","guid":{"rendered":"https:\/\/jobelyn.com.ng\/ng\/?p=6749"},"modified":"2024-04-18T03:19:00","modified_gmt":"2024-04-18T03:19:00","slug":"why-conventional-orthodox-drug-systems-are-not-working","status":"publish","type":"post","link":"https:\/\/jobelyn.com.ng\/ng\/2021\/12\/27\/why-conventional-orthodox-drug-systems-are-not-working\/","title":{"rendered":"WHY CONVENTIONAL ORTHODOX DRUG SYSTEMS ARE NOT WORKING"},"content":{"rendered":"
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The major problem with the current approach is that conventional medicine is restricted to chemical drugs targeted to cancer cells. These drugs are not capable of discriminating between cancer and other healthy cells and so the drugs which are cytotoxic destroy both types of cells resulting in very dangerous side effects which may be worse than the cancer itself. The principles of cyclo-oxygenase and cox selectivity comes to mind. Scientists have not yet discovered a conventional drug that is cox selective. Once this is achieved, most health problems would be solved.<\/p>\n

The point I am trying to present is better illustrated by reference to the abstract from a book written by a renowned scientist. The title of the book is CONCEPTS AND MISCONCEPTIONS OF DRUGS DISCOVERY. The abstract is reproduced below:<\/p>\n

Many new technologies start as science fiction ideas. The \u201cideal drug\u201d that Paul Ehrlich proposed in 1906 was based on a clear definition of its purpose\u2014to be 100% effective all the time and have no undesirable side effects. Much effort has been expended in this direction, especially in the last 50 years or so, but this concept of a \u201cmagic bullet\u201d remains only science fiction.<\/p>\n

A fundamental law of physics states that \u201c\u2026only light of energy that can cause transitions from one existing energy level to another will be absorbed\u201d. A similar rule applies to the action of drugs\u2014for a drug to act on a given disease, it needs to interact or bind with the molecular structures associated with the disease, and elicit a therapeutic effect. Unfortunately, in most cases, the same structures to which the drug can bind are present not only in the disease, but also in normal cells; this makes it obvious why delivering drugs solely to the sites of a disease is important.<\/p>\n

We expect all drugs to be beneficial and not harmful. Unfortunately, this is not very often the case. Here is why.<\/p>\n

The ultimate task of drug delivery is to induce drug action only on diseased cells (for example, cancer cells). Such a system must avoid the body\u2019s natural defense mechanisms and deposit the drug at its intended site of action. From that point on, the fate of the drug is determined by its own physicochemical and biological properties. Only drugs with the appropriate pharmacokinetic properties will benefit from the application of an appropriate delivery system.<\/p>\n

Why is targeting the disease important? Let us take cancer as an example.<\/p>\n

Cancer is the second most lethal disease in the US: some 1.7 million Americans were diagnosed with cancer in 2018, of whom around 600,000 died. Over 15 million Americans cancer survivors are alive today.<\/p>\n