{"id":7141,"date":"2024-04-18T03:18:59","date_gmt":"2024-04-18T03:18:59","guid":{"rendered":"https:\/\/jobelyn.com.ng\/ng\/?p=7141"},"modified":"2024-04-18T03:18:59","modified_gmt":"2024-04-18T03:18:59","slug":"are-polyphenol-antioxidants-at-the-root-of-medicinal-plant-anti-cancer-success","status":"publish","type":"post","link":"https:\/\/jobelyn.com.ng\/ng\/2024\/04\/18\/are-polyphenol-antioxidants-at-the-root-of-medicinal-plant-anti-cancer-success\/","title":{"rendered":"Are polyphenol antioxidants at the root of medicinal plant anti-cancer success?"},"content":{"rendered":"<p>&nbsp;<\/p>\n<h1 id=\"screen-reader-main-title\" class=\"Head u-font-serif u-h2 u-margin-s-ver\"><span class=\"title-text\">Are polyphenol antioxidants at the root of medicinal plant anti-cancer success?<\/span><\/h1>\n<p><!--more--><\/p>\n<div id=\"banner\" class=\"Banner\">\n<div class=\"wrapper truncated\">\n<div class=\"AuthorGroups text-xs\">\n<div id=\"author-group\" class=\"author-group\"><span class=\"sr-only\">Author links open overlay panel<\/span><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0378874118316143?via%3Dihub#!\" name=\"bau0005\"><span class=\"content\"><span class=\"text given-name\">A.B.<\/span><span class=\"text surname\">Oyenihi<\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0378874118316143?via%3Dihub#!\" name=\"bau0010\"><span class=\"content\"><span class=\"text given-name\">C.<\/span><span class=\"text surname\">Smith<\/span><\/span><\/a><\/div>\n<\/div>\n<\/div>\n<p><button id=\"show-more-btn\" class=\"button show-hide-details button-primary\" type=\"button\" data-aa-button=\"icon-expand\"><span class=\"button-text\">Show more<\/span><\/button><\/p>\n<div class=\"banner-options u-padding-xs-bottom\">\n<div id=\"social\" class=\"Social u-display-inline-block\">\n<div id=\"social-popover\" class=\"popover social-popover\">\n<div id=\"popover-trigger-social-popover\"><button class=\"button button-anchor\" type=\"button\" aria-expanded=\"false\" aria-haspopup=\"true\"><span class=\"button-text\">Share<\/span><\/button><\/div>\n<\/div>\n<\/div>\n<div id=\"export-citation\" class=\"ExportCitation u-display-inline-block\">\n<div id=\"export-citation-popover\" class=\"popover export-citation-popover\">\n<div id=\"popover-trigger-export-citation-popover\"><button class=\"button button-anchor\" type=\"button\" aria-expanded=\"false\" aria-haspopup=\"true\"><span class=\"button-text\">Cite<\/span><\/button><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"article-identifier-links\" class=\"ArticleIdentifierLinks\"><a class=\"doi\" title=\"Persistent link using digital object identifier\" href=\"https:\/\/doi.org\/10.1016\/j.jep.2018.09.037\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"Persistent link using digital object identifier\">https:\/\/doi.org\/10.1016\/j.jep.2018.09.037<\/a><a class=\"rights-and-content\" href=\"https:\/\/s100.copyright.com\/AppDispatchServlet?publisherName=ELS&amp;contentID=S0378874118316143&amp;orderBeanReset=true\" target=\"_blank\" rel=\"noreferrer noopener\">Get rights and content<\/a><\/div>\n<section class=\"ReferencedArticles\"><\/section>\n<section class=\"ReferencedArticles\"><\/section>\n<div id=\"preview-section-abstract\">\n<div class=\"PageDivider\"><\/div>\n<div id=\"abstracts\" class=\"Abstracts u-font-serif\">\n<div id=\"ab0010\" class=\"abstract author\">\n<h2 class=\"section-title u-h3 u-margin-l-top u-margin-xs-bottom\">Abstract<\/h2>\n<div id=\"abs0010\">\n<h3 id=\"sect0010\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Ethnopharmacological relevance<\/h3>\n<p id=\"sp0035\">Given the severe side effects associated with most of the conventional cancer medications, as well as the expanding body of evidence indicating secondary toxicity of these drugs, individuals with cancer are increasingly turning to natural alternatives. Similarly, the pharmaceutical industry is in search of natural products to treat cancer. An understanding of the specific active components in plant products with which anti-cancer efficacy is achieved is required for this research to move forward.<\/p>\n<\/div>\n<div id=\"abs0015\">\n<h3 id=\"sect0015\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Aim of the study<\/h3>\n<p id=\"sp0040\">To integrate data from cancer-relatestudies on plant-derived products or extracts, to elucidate whether these products may have similar active ingredients and\/or mechanisms of action, that can explain their efficacy. This review also includes a discussion of the methodological complexities and important considerations involved in accurate isolation and characterisation of active substances from plant material.<\/p>\n<\/div>\n<div id=\"abs0020\">\n<h3 id=\"sect0020\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Conclusions<\/h3>\n<p id=\"sp0045\">From the literature reviewed, most plant products with consistently reported anti-cancer efficacy contains high levels of polyphenols or other potent antioxidants and their mechanisms of action correlate to that reported for isolated antioxidants in the context of cancer. This suggests that natural products may indeed become the panacea against this chronic disease \u2013 either as therapeutic medicine strategy or to serve as templates for the design of novel synthetic drugs. The recommendation is made that antioxidant activity of plant actives and especially polyphenols, should be the focus of anti-cancer drug discovery initiatives. Lastly, researchers are advised to exploit current techniques of chemical compound characterisation when investigating polyphenol-rich plants to enable the easy consolidation of research findings from different laboratories.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Are polyphenol antioxidants at the root of medicinal plant anti-cancer success?<\/p>\n","protected":false},"author":93,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7141","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts\/7141","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/users\/93"}],"replies":[{"embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/comments?post=7141"}],"version-history":[{"count":1,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts\/7141\/revisions"}],"predecessor-version":[{"id":7142,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts\/7141\/revisions\/7142"}],"wp:attachment":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/media?parent=7141"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/categories?post=7141"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/tags?post=7141"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}