{"id":7368,"date":"2024-04-18T03:18:59","date_gmt":"2024-04-18T03:18:59","guid":{"rendered":"https:\/\/jobelyn.com.ng\/ng\/?p=7368"},"modified":"2024-04-18T03:18:59","modified_gmt":"2024-04-18T03:18:59","slug":"is-diabetes-curable","status":"publish","type":"post","link":"https:\/\/jobelyn.com.ng\/ng\/2024\/04\/18\/is-diabetes-curable\/","title":{"rendered":"Is Diabetes curable?"},"content":{"rendered":"
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  1. <\/li>\n<\/ol>\n

    Diabetes Mellitus (DM) and Alzheimer’s disease (AD) are two prevalent diseases in modern societies, which are caused mainly by current lifestyle, aging and genetic alterations. It has already been demonstrated that these two diseases are associated, since individuals suffering from DM are prone to develop AD. Conversely, it is also known that individuals with AD are more susceptible to DM, namely type 2 diabetes (T2DM). Therefore, these two pathologies, although completely different in terms of symptomatology, end up sharing several mechanisms at the molecular level, with the most obvious be-ing the increase of oxidative stress and inflammation.<\/p>\n

    Polyphenols are natural compounds widely spread in fruits and vegetables whose dietary intake has been considerably proportional to the incidence of DM and AD. So, it is believed that this group of phytochemicals may have preventive and therapeutic potential, not only by reducing the risk and delaying the development of these pathologies, but also by improving brain\u2019s metabolic profile and cognitive function<\/p>\n

    https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6712293\/<\/a><\/p>\n

    Recently, Sorghum bicolor supplement was listed in the drug dictionary of the National Cancer Institute and described described as being rich in Polyphenols and phenolic compounds with the potential for antioxidant,anti-inflammatory, immunomodulating and chemopreventive capabilities<\/p>\n

    https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-drug\/def\/sorghum-bicolor-supplement<\/a><\/p>\n

    In an animal model, the scientists from the University of Ibadan led by Professor Umukoro demonstrated that that Sorghum bicolor<\/p>\n

    Jobelyn has anti-amnesic activity and might offer some promising effects for the treatment of memory deficits. Although more studies are necessary, the present data suggest that the anti-amnesic property of Sorghum bicolor supplement Jobelyn appears to be mediated through the scavenging of reactive oxygen species and\/or inhibition of their formation.<\/p>\n

    https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4202556\/<\/a><\/p>\n

     <\/p>\n

    Sorghum extract exerts an anti-diabetic effect by improving insulin sensitivity via PPAR-\u03b3 in mice fed a high-fat diet<\/h5>\n

    https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3439576\/<\/a><\/p>\n

     <\/p>\n

    Network pharmacology of bioactives from\u00a0Sorghum bicolor<\/em>\u00a0with targets related to diabetes mellitus<\/strong><\/h5>\n

    https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7774932\/<\/a><\/p>\n

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    1. Preadministration of Fermented Sorghum Diet Provides Protection against Hyperglycemia-Induced Oxidative Stress and Suppressed Glucose Utilization in Alloxan-Induced Diabetic Rats<\/li>\n<\/ol>\n

      https:\/\/www.frontiersin.org\/articles\/10.3389\/fnut.2018.00016\/full<\/a><\/p>\n

      http:\/\/www.eurekaselect.com\/article\/95778<\/p>\n

      Sorghum (Sorghum bicolor) Extract Affects Plasma Lipid Metabolism and Hepatic Macrophage Infiltration in Diabetic Rats<\/h5>\n

      http:\/\/www.eurekaselect.com\/article\/95778<\/a><\/p>\n

       <\/p>\n

      Anti-diabetic effect of sorghum extract on hepatic gluconeogenesis of streptozotocin-induced diabetic rats<\/h5>\n

      https:\/\/nutritionandmetabolism.biomedcentral.com\/articles\/10.1186\/1743-7075-9-106<\/a><\/p>\n

       <\/p>\n

       <\/p>\n

      Grain sorghum muffin reduces glucose and insulin responses in men<\/h5>\n

       <\/p>\n

      https:\/\/pubs.rsc.org\/en\/content\/articlehtml\/2014\/fo\/c3fo60432b<\/a><\/p>\n

       <\/p>\n

      THE POTENTIAL OF SORGHUM BICOLOR L. AS A BLOOD GLUCOSE LOWERING AGENT : A REVIEW<\/h5>\n

       <\/p>\n

      https:\/\/journal.uin-alauddin.ac.id\/index.php\/kesehatan\/article\/view\/18181<\/a><\/p>\n

      Sorghum halepense<\/em>\u00a0(L.) Pers rhizomes inhibitory potential against diabetes and free radicals<\/h5>\n

       <\/p><\/blockquote>\n

      https:\/\/clinphytoscience.springeropen.com\/articles\/10.1186\/s40816-021-00259-3<\/a><\/p>\n

       <\/p>\n

       <\/p>\n","protected":false},"excerpt":{"rendered":"

      Diabetes Mellitus (DM) and Alzheimer’s disease (AD) are two prevalent diseases in modern societies, which are caused mainly by current lifestyle, aging and genetic alterations. It has already been demonstrated that these two diseases are associated, since individuals suffering from DM are prone to develop AD. Conversely, it is also known that individuals with AD…<\/p>\n","protected":false},"author":93,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7368","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts\/7368","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/users\/93"}],"replies":[{"embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/comments?post=7368"}],"version-history":[{"count":1,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts\/7368\/revisions"}],"predecessor-version":[{"id":7369,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts\/7368\/revisions\/7369"}],"wp:attachment":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/media?parent=7368"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/categories?post=7368"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/tags?post=7368"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}