{"id":7725,"date":"2024-04-18T03:18:58","date_gmt":"2024-04-18T03:18:58","guid":{"rendered":"https:\/\/jobelyn.com.ng\/ng\/?p=7725"},"modified":"2024-04-18T03:18:58","modified_gmt":"2024-04-18T03:18:58","slug":"scientific-publications-on-jobelyn-other-products-updated","status":"publish","type":"post","link":"https:\/\/jobelyn.com.ng\/ng\/2024\/04\/18\/scientific-publications-on-jobelyn-other-products-updated\/","title":{"rendered":"SCIENTIFIC PUBLICATIONS ON JOBELYN & OTHER PRODUCTS UPDATED"},"content":{"rendered":"

INDEX TO PUBLISHED ARTICLES FOR WEBSITE<\/a><\/p>\n

Polyphenol Rich Nutritional Supplement Derived from the West African Sorghum Bicolor Leaf Sheaths Has Evidence-Based Efficacy and Health Promoting Effects<\/u><\/strong><\/p>\n

\u00a0<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n

Sub-acute toxicological effects of Jobelyn\u00ae on pregnant albino rats American Institute of Physics <\/strong><\/p>\n

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  1. Adebayo, A.H.; Yakubu, O.F.; Egbung, G.E.; Williams, O.I.; Okubena, O. Sub-acute toxicological effects of Jobelyn\u00ae on pregnant albino rats American Institute of Physics 2018, 1954:030018 org\/10.1063\/1.5033398.<\/em><\/a><\/li>\n<\/ol>\n

     <\/p>\n

    The West African Sorghum bicolor leaf sheath extract Jobelyn\u00ae and its diverse therapeutic potentials.<\/strong><\/p>\n

      \n
    1. Okubena, O.; Makanjuola, S.; Ajonuma, L.C.; Dosunmu, A.; Umukoro, S.; Erah, P.O. The West African Sorghum bicolor leaf sheath extract Jobelyn\u00ae and its diverse therapeutic potentials. MOJ Drug Design & Development Therapy 2018, 2, 1-10. DOI: 10.15406\/mojddt.2018.02.00025.<\/em><\/a><\/li>\n<\/ol>\n

      Apigenin and apigeninidin isolates from the Sorghum bicolor leaf targets inflammation via cyclooxygenase\u20102 and prostaglandin\u2010E2 blockade. <\/strong><\/p>\n

        \n
      1. Makanjuola, S.B.L.; Ogundaini, A.O.; Ajonuma, L.C.; Dosunmu, A. Apigenin and apigeninidin isolates from the Sorghum bicolor leaf targets inflammation via cyclooxygenase\u20102 and prostaglandin\u2010E2 blockade. Clin Transplant<\/em>. 2018, 21, 1487\u2010<\/em><\/a><\/li>\n<\/ol>\n

        The influence of African herbal formular on the haematological parameters of trypanosome infected rats.<\/strong><\/p>\n

          \n
        1. Okochi VI, Okpuzor J, Okubena MO, Awoyemi AK. The influence of African herbal formular on the haematological parameters of trypanosome infected rats. J. Biotech. 2003, 2, 312\u2013316.<\/em><\/a><\/li>\n<\/ol>\n

          Erah, P.O.; Asonye, C.C, Okhamafe, A.O. Response of trypanosoma brucei-induced anaemia to a commercial herbal preparation.<\/strong><\/p>\n

            \n
          1. Erah, P.O.; Asonye, C.C, Okhamafe, A.O. Response of trypanosoma brucei-induced anaemia to a commercial herbal preparation.<\/em> Afr. J. Biotechnol, 2003, 2, 307\u2013311.<\/em><\/a><\/li>\n<\/ol>\n

             <\/p>\n

            How an African-made dietary supplement promises to revolutionize medical treatment.<\/strong><\/p>\n

            \u00a0Nnaji, M. How an African-made dietary supplement promises to revolutionize medical treatment. The frican Courier (Germany).\u00a0<\/em>https:\/\/www.theafricancourier.de\/africa\/<\/em><\/a><\/p>\n

            Drug Dictionary of the National Cancer Institute, USA<\/strong><\/p>\n

            An herbal-based nutritional supplement containing the leaf sheaths of the plant Sorghum bicolor, with potential antioxidant, anti-inflammatory, chemopreventive and immunomodulating activities<\/strong><\/p>\n

            Drug Dictionary of the National Cancer Institute, USA (https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-drug\/def\/sorghum-bicolor-supplement<\/a><\/p>\n

            Umukoro, S.; Oghwere, E.E.; Ben-Azu, B.; Owoeye, O.; Ajayi, A.M.; Omorogbe, O.; Okubena, O. Jobelyn\u00ae ameliorates neurological deficits in rats with ischemic stroke through inhibition of release of pro-inflammatory cytokines and NF-\u0138B signaling pathway<\/strong><\/p>\n

            Umukoro, S.; Oghwere, E.E.; Ben-Azu, B.; Owoeye, O.; Ajayi, A.M.; Omorogbe, O.; Okubena, O. Jobelyn\u00ae ameliorates neurological deficits in rats with ischemic stroke through inhibition of release of pro-inflammatory cytokines and NF-\u0138B signaling pathway Pathophysiology 2018, 26, 77-88.<\/a><\/p>\n

            West African Sorghum bicolor leaf sheaths have anti-inflammatory and immune-modulating properties in vitro<\/strong>.<\/p>\n

            Benson, K.F.; Beaman, J.L.; Ou, B.; Okubena, A.; Okubena, O.; Jensen G.S. West African Sorghum bicolor leaf sheaths have anti-inflammatory and immune-modulating properties in vitro. Journal of Medicinal Foods 2013, 16, 230\u2013238.<\/a><\/p>\n

            Jobelyn\u00ae ameliorates neurological deficits in rats with ischemic stroke through inhibition of release of pro-inflammatory cytokines and NF-\u0138B signaling pathway\u00a0<\/strong><\/p>\n

            Umukoro, S.; Oghwere, E.E.; Ben-Azu, B.; Owoeye, O.; Ajayi, A.M.; Omorogbe, O.; Okubena, O. Jobelyn\u00ae ameliorates neurological deficits in rats with ischemic stroke through inhibition of release of pro-inflammatory cytokines and NF-\u0138B signaling pathway Pathophysiology 2018, 26, 77-88.<\/a><\/p>\n

            \u00a0Neuroprotective effect of Jobelyn\u00ae in the hippocampus of alcoholic rat is mediated in part by alterations in GFAP and NF protein expressions<\/strong>.<\/p>\n

            \u00a0Oyinbo, C.A.; Dare, W.N.; Avwioro, O.G.; Igbigbi, P.S. Neuroprotective effect of Jobelyn\u00ae in the hippocampus of alcoholic rat is mediated in part by alterations in GFAP and NF protein expressions. Advances in Biological Research 2015, 9, 305-317.<\/a><\/p>\n

            \u00a0Clinical efficacy of a West African Sorghum bicolor-based traditional herbal preparation Jobelyn shows increased hemoglobin and CD4+ T-lymphocyte counts in HIV-positive patients.<\/strong><\/p>\n

            Ayuba, G.I.; Jensen, G.S.; Benson, K.F.; Okubena, A.M.; Okubena, O.\u00a0 Clinical efficacy of a West African Sorghum bicolor-based traditional herbal preparation Jobelyn shows increased hemoglobin and CD4+ T-lymphocyte counts in HIV-positive patients. \u00a0J Altern Complement Med. 2014, 20, 53\u201356.<\/a><\/p>\n

            An open-label, randomized, parallel-group comparative study of the efficacy of Sorghum bicolor extract in preoperative<\/strong> anemia. <\/strong><\/p>\n

            Tayo ,\u00a0 A.O.; \u00a0Dosunmu, O.; \u00a0Akinola \u00a01 ,\u00a0 I.O.; Adewunmi, A.; \u00a0Oloyede ,\u00a0O.A.; Akinbami,\u00a0 A.A.; Osikomaiya ,\u00a0B.I.; Makanjuola, S.B.L. An open-label, randomized, parallel-group comparative study of the efficacy of Sorghum bicolor extract in preoperative anemia. Nutrition. 2007, 33, 113\u2013117.<\/a><\/p>\n

            Jobelyn\u00ae exhibited anti-inflammatory, antioxidant, and membrane-stabilizing activities in experimental models,<\/strong><\/p>\n

            Umukoro, S.; Oluwole, O.G.;\u00a0 Eduviere, A.T.;\u00a0 Omogbiya,\u00a0 A.; \u00a0 Ajayi,\u00a0 A.M. Jobelyn\u00ae exhibited anti-inflammatory, antioxidant, and membrane-stabilizing activities in experimental models, J. Basic Clin. Physiol. Pharmacol. 2015, 26, 501\u2013508.<\/a><\/p>\n

            Omorogbe, O.; Ajayi, A.M.; Ben-Azu, B.; Oghwere, E.E.;\u00a0 Adebesin, A.;\u00a0 Aderibigbe, A.O.; Okubena, O.; Umukoro, S. Jobelyn\u00ae attenuates inflammatory responses and neurobehavioural deficits associated with complete Freund-adjuvant-induced arthritis in mice. & Pharmacother. 2018, 98, 585\u2013593.<\/a><\/p>\n

            Jobelyn\u00ae attenuates inflammatory responses and neurobehavioural deficits associated with complete Freund-adjuvant-induced arthritis in mice.<\/strong><\/p>\n

              \n
            1. Oyinbo, C.A.; Igbigbi, P.S.; Avwioro, O.G. Jobelyn\u00aesupplement lowered neuronal degeneration: significance of altered p53 and \u0264-Enolase protein expressions in prefrontal cortex of rat exposed to ethanol. Annals of Neurosciences 2016, 23, 139\u2013148.<\/a><\/li>\n<\/ol>\n

              Antioxidant property of Jobelyn\u00ae as the possible mechanism underlying its anti-amnesic effect in rodents<\/strong><\/p>\n

              Umukoro, S.; Ugbomah, A.; Aderibigbe, A.; Omogbiya, A. Antioxidant property of Jobelyn\u00ae as the possible mechanism underlying its anti-amnesic effect in rodents. Basic and Clinical Neurosci. 2013, 4, 42-49.<\/a><\/p>\n

              Jobelyn\u00ae extends the life span and improves motor function in Drosophila melanogaster exposed to lipopolysaccharide via augmentation of antioxidant status.<\/strong><\/p>\n

              John, R.; Abolaji, A.O.; Adedara, A.O.; Ajayi, A.M.; Aderibigbe, A.O.; Umukoro, S. Jobelyn\u00ae extends the life span and improves motor function in Drosophila melanogaster exposed to lipopolysaccharide via augmentation of antioxidant status. Metabolic Brain Disease 2022, 37, 1031-1040.<\/a><\/p>\n

              Newly isolated compounds \u00a0from West African Sorghum bicolor leaf sheaths Jobelyn\u00ae show potential in cancer immunosurveillance<\/strong>.<\/p>\n

              Makanjuola, S.B.L.;\u00a0 \u00a0Dosunmu,\u00a0 D.;\u00a0 \u00a0Ajonuma, L.;\u00a0 \u00a0Ogundaini,\u00a0 A.; Okubena, O. Newly isolated compounds \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0from West African Sorghum bicolor leaf sheaths Jobelyn\u00ae show potential in cancer immunosurveillance. J. Cancer Res. & Ther. 2016,\u00a0 4, 31-37.<\/a><\/p>\n

              Jobelyn, a sorghum-based nutritional supplement attenuates unpredictable chronic mild stress-induced memory deficits in mice.<\/strong><\/p>\n

              Umukoro, S.; Omorogbe, O.; Aluko, O.M.; Eduviere, T.A.; Owoeye, O.; Oluwole, O.G. Jobelyn, a sorghum-based nutritional supplement attenuates unpredictable chronic mild stress-induced memory deficits in mice. Journal of Behavioral and Brain Sci. 2015, 5, 586-597.<\/a><\/p>\n

              Antidepressant-like property of Jobelyn\u00ae an African unique herbal formulation in mice. <\/strong><\/p>\n

              Umukoro, S.; Eduviere, A.T.; Aladeokin, A.C.; Olugbemide, A.\u00a0 Antidepressant-like property of Jobelyn\u00ae an African unique herbal formulation in mice. Drug Res. 2014, 64, 146-150.<\/a><\/p>\n

              New Highly Stable Dimeric 3-Deoxyanthocyanidin Pigments from Sorghum bicolor Leaf Sheath<\/strong><\/p>\n

              Bhimalingeswarappa Geera, Leonnard O. Ojwang, and Joseph M. Awika \u2026\u2026.New Highly Stable Dimeric 3-Deoxyanthocyanidin Pigments from Sorghum bicolor Leaf Sheath\u2026\u2026..Journal of Food Science _ Vol. 77, Nr. 5, 2012 doi: 10.1111\/j.1750-3841.2012.02668.x\u2026\u2026\u2026\u2026\u2026\u2026\u2026..<\/a><\/p>\n

              Jobelyn pretreatment ameliorates symptoms of psychosis in experimental models <\/strong><\/p>\n

              Itivere Adrian Omogbiya, Adegbuyi Oladele Aderibigbe and Adewale Ganiyu Bakre Jobelyn pretreatment ameliorates symptoms of psychosis in experimental models DOI 10.1515\/jbcpp-2012-0073 J Basic Clin Physiol Pharmacol 2013<\/a><\/p>\n

              Thermal stability of 3-deoxyanthocyanidin pigments\u00a0<\/strong><\/p>\n

              Thermal stability of 3-deoxyanthocyanidin pigments Liyi Yang , Linda Dykes , Joseph M. Awika Journal of Food Chemistry http:\/\/dx.doi.org\/10.1016\/j.foodchem.2014.03.105<\/a><\/p>\n

              Toxicological Profiles of Commercial Herbal Preparation, Jobelyn\u00ae<\/strong><\/p>\n

              Toxicological Profiles of Commercial Herbal Preparation, Jobelyn\u00ae nternational Journal of Health Research, December 2009; 2(4): 369-374 \u00a9 Poracom Academic Publishers. All rights reserved. Available at http:\/\/www.ijhr.orgR<\/a><\/p>\n

              Patients with Sickle Cell Anemia<\/strong> \u00a0The short time effect of extract of Sorghum bicolor (Jobelyn) on the haematological parameters of<\/strong><\/p>\n

              Dosunmu A. O. et al., Journal Of Harmonized Research in Medical & Health Sci.3(4), 2016, 3(4),296-302The short time effect of extract of Sorghum bicolor (Jobelyn) on the haematological parameters of Patients with Sickle Cell Anemia.<\/a><\/p>\n

               <\/p>\n

              Hepatoprotective and antioxidant activities of Hepacare\u00ae, a herbal formulation against carbon tetrachloride-induced liver injury. <\/strong><\/p>\n

              Ishola IO, Akinyede AA, Robert AK, Omilabu SA. Hepatoprotective and antioxidant activities of Hepacare\u00ae, a herbal formulation against carbon tetrachloride-induced liver injury. Drug Res (Stuttg). 2015 Jan;65(1):30-9. doi: 10.1055\/s-0034-1371829. Epub 2014 Apr 7. PMID: 24710964.<\/a><\/p>\n

              Haematopoietic induction and hepatic protective roles of Hepacare\u00ae in CCl4-induced hepatic damaged rats<\/strong><\/p>\n

              Haematopoietic induction and hepatic protective roles of Hepacare\u00ae in CCl4-induced hepatic damaged rats Abiodun Humphrey Adebayo1 & Omolara Faith Yakubu1 & Oluwatobi Samuel Adegbite 1 & Olajuwon Okubena2Haematopoietic induction and hepatic protective roles of Hepacare\u00ae in CCl4-induced hepatic damaged rats<\/a><\/p>\n

               <\/p>\n

              Evaluation of antimalarial and biochemical profiles of Abaleria Plasmodium berghei-infected mice<\/strong><\/p>\n

              Abiodun Humphrey Adebayo and Omolara Faith Yakubu and Jacob O. Popoola and L. David and Gloria Nwabugwu Okenze and Amarachi Grace Agbafor and Olajuwon Okubena<\/a><\/p>\n

              Evaluation of antimalarial and biochemical profiles of Abaleria Plasmodium berghei-infected mice<\/a><\/p>\n

              Antimicrobial and Toxicity Studies on Holisa Herbal Formulation<\/strong><\/p>\n

              Adebayo AH, Yakubu OF, Ezekiel-Hart ES, Okubena O. Antimicrobial and Toxicity Studies on Holisa Herbal Formulation. Trop J Nat Prod Res. 2021; 5(5):983-987. http:\/\/www.doi.org\/10.26538\/tjnpr\/v5i5.30<\/strong><\/p>\n

              https:\/\/www.tjnpr.org\/viewarticle.aspx?articleid=1583<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

              INDEX TO PUBLISHED ARTICLES FOR WEBSITE Polyphenol Rich Nutritional Supplement Derived from the West African Sorghum Bicolor Leaf Sheaths Has Evidence-Based Efficacy and Health Promoting Effects \u00a0 \u00a0 Sub-acute toxicological effects of Jobelyn\u00ae on pregnant albino rats American Institute of Physics Adebayo, A.H.; Yakubu, O.F.; Egbung, G.E.; Williams, O.I.; Okubena, O. Sub-acute toxicological effects of…<\/p>\n","protected":false},"author":93,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7725","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts\/7725","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/users\/93"}],"replies":[{"embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/comments?post=7725"}],"version-history":[{"count":1,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts\/7725\/revisions"}],"predecessor-version":[{"id":7727,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/posts\/7725\/revisions\/7727"}],"wp:attachment":[{"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/media?parent=7725"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/categories?post=7725"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jobelyn.com.ng\/ng\/wp-json\/wp\/v2\/tags?post=7725"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}