SORGHUM BICOLOR SUPPLEMENT – IMMUNE MODULATOR
The immune enhancing capabilities of Sorghum bicolor supplement is better described as immunomodulating by the National Cancer Institute. As if by AI (Artificial Intelligence), some components (cytokines and chemokines) of Sorghum bicolor supplement, Jobelyn, regulate the immune system by means of pro and anti-inflammatory processes to achieve chemopreventive capabilities.
Sorghum bicolor supplement
An herbal-based nutritional supplement containing the leaf sheaths of the plant Sorghum bicolor, with potential antioxidant, anti-inflammatory, chemopreventive and immunomodulating activities. Sorghum bicolor supplement contains various phytochemicals, including phenolic acids and polyphenols such as proanthocyanidins. Sorghum bicolor supplement is particularly rich in 3-deoxyanthocyanins, such as luteolinidin and apigeninidin, and appears to induce apoptosis and inhibit cell proliferation in cancer cells through the stimulation of various apoptosis promoter genes and the downregulation of certain apoptosis inhibitor genes. In addition, due to the strong antioxidant nature of the phytochemicals, these compounds are able to scavenge free radicals and prevent tissue damage. Also, intake of this supplement modulates the immune system by both increasing the activity of natural killer (NK) cells and initiating the activation of macrophages.
This is demonstrated in the scientific research carried out by NIS Laboratory in the US. CLICK
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598435/
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Open in new tab The immune enhancing capabilities of Sorghum bicolor supplement is better described as immunomodulating by the National Cancer Institute. As if by AI (Artificial Intelligence), some components (cytokines and chemokines) of Sorghum bicolor supplement, Jobelyn, regulate the immune system by means of pro and anti-inflammatory processes to achieve chemopreventive capabilities. This is demonstrated in the scientific research carried out by NIS Laboratory in the US.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598435/
| Changes in Cytokine Levels After Exposure of Peripheral | |||||
| Blood Mononuclear Cells to SBLS Ethanol Extract | |||||
| Target | MFI (untreated)a | MFI (SBLS)b | Fold changec | Concentration (ng/mL)d | |
| IL-1β | 1 | 9 | 9 | <12.07 | |
| IL-1Rα | 2.5 | 21 | 8 | 72.58 | |
| IL-6 | 6.5 | 1129.5 | 174 | 430.68 | |
| IL-7 | 0.75 | 4.75 | 6 | 16.73 | |
| CXCL8 | IL-8 | 660.25 | 8511.5 | 13 | >388.9 |
| CSIF | IL-10 | 0.5 | 7.5 | 15 | <30.25 |
| IL-12 | 2.5 | 11.5 | 5 | 13.08 | |
| IL-13 | 0.5 | 2.5 | 5 | <8.78 | |
| IL-15 | 1 | 8.5 | 9 | <11.61 | |
| CCL2 | MCP1 | 13 | 1890.25 | 145 | >592.51 |
| CCL3 | MIP-1α | 0.5 | 120.5 | 241 | 62.97 |
| CCL4 | MIP-1β | 2.5 | 418.75 | 168 | 127.27 |
| CCL5 | RANTES | 156 | 337.25 | 2 | 94.84 |
| IFN-α | 1 | 12 | 12 | 33.38 | |
| CXCL10 | IP10 | 1 | 5.5 | 6 | <1.62 |
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The NCI descibes Sorghum bicolor supplement as An herbal-based nutritional supplement containing the leaf sheaths of the plant Sorghum bicolor, with potential antioxidant, anti-inflammatory, chemopreventive and immunomodulating activities. Sorghum bicolor supplement contains various phytochemicals, including phenolic acids and polyphenols such as proanthocyanidins. Sorghum bicolor supplement is particularly rich in 3-deoxyanthocyanins, such as luteolinidin and apigeninidin, and appears to induce apoptosis and inhibit cell proliferation in cancer cells through the stimulation of various apoptosis promoter genes and the downregulation of certain apoptosis inhibitor genes. In addition, due to the strong antioxidant nature of the phytochemicals, these compounds are able to scavenge free radicals and prevent tissue damage. Also, intake of this supplement modulates the immune system by both increasing the activity of natural killer (NK) cells.
